In the early 80's, bows were considerably slower than now. My pins were set at 20, 30, 40, and 50 in those days. I missed more that one deer because in the excitement of the moment, I'd use the wron pin.
Today, with hunting arrow speeds easily in excess of 250 fps, I RARELY if ever use the wrong pin. But now, my pins are set at 25, 35, and 45 yards. It also helps me to get a "sight picture" very quickly by simply having a top, middle, and bottom pin.
My set up shoots fairly flat from 8 yards to 27 yards, with about a 4 inch variation from top pin (8 yards) to bottom pin (27 yards). This way, it keeps it simple for me. I have always been bad at judging distance, especially from 20 feet up a tree. But I can quickly use my rangefinder (or in the old days, pace off prior to my climb), 25 yards in at least 4 directions. This way, anything outside my 25 yard mark I hold a hair high, or low if inside my marker.
The vast majority of all of our shots (hundreds) is 19 yards.
Good luck and remember to aim low!