Now your arrow is not coming off the rest sideways you should pick up a very valuable 1-2fps! LOL
Yes, if it is not setup correctly. On most every Mathews the arrow should be centered at 12/16ths off of the riser�give or take 1/16th either side, and the arrow should be centered of the berger hole nock up 1/8th" to 1/4" with a bow square. As long as your cams are in time, and your spined correctly you should have a bullet hole at 6ft and 10yds.
Now that you have a good tear, I would strongly advise you to walk back tune and broadhead tune. Heck, you might even pick up an additional 1-2fps doing that as well.