I use IMR4895 in my M1 Garand, Johnson 1941 and 1903a3. I just load 47.5 or 48.0 gr. behind a 147 gr. M2 or Hornady 150 gr. But, in full power hunting loads, in my opinion, .30-06 really needs a slower burning powder. Sometimes max pressure will be met before good velocity. My IMR4895 load with Hornady 150 gr. and 49.5 gr. hits 2750 fps. Basically a .308 load.