I wonder... how much of the population decline was due to CWD and how much was due to the 'gloves off', kill everything management approach?
With CWD, animals are not going to live as long... which means annual mortality from the disease will approach 10 to 15% (I'm assuming 10 to 15% have had the disease 2 to 4 years and therefore die of it). If annual mortality from hunting increases due to regulation changes (ESPECIALLY IF AGE STRUCTURES OF KILLED DOES IS DECLINING), the population will decline and perhaps even collapse.
In herds with CWD, since it's impossible to eradicate CWD, it becomes even more imperative to selectively harvest only the oldest animals... allowing the younger (esp does) to reproduce.