I sight my top pin to be 1" high at 20 yards which gives me a 30 yard zero. Anything from 0-20 yards will be a little higher but still a lethal shot on a deer if you aim for the center of the chest.
My second pin is zeroed at 40 yards and my third pin is zeroed for 50 yards.
I have and will take a 50 yard shot at a deer under the right circumstances, i.e. the deer is at ease and standing still, is broadside or slightly quartering away, I have a clear shooting lane and I have ranged the deer and know exactly how far away it is.
I much prefer a closer shot preferably under 30 yards though and if I see a deer at 50 yards or so that is feeding or walking closer I will wait for that closer shot.